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Analysis of nucleosome positioning determined by DNA helix curvature in the human genome

BACKGROUND: Nucleosome positioning has an important role in gene regulation. However, dynamic positioning in vivo casts doubt on the reliability of predictions based on DNA sequence characteristics. What role does sequence-dependent positioning play? In this paper, using a curvature profile model, n...

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Autors principals: Liu, Hongde, Duan, Xueye, Yu, Shuangxin, Sun, Xiao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037905/
https://ncbi.nlm.nih.gov/pubmed/21269520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-72
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