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Hypocalcemia increases and hypercalcemia decreases the steady-state level of parathyroid hormone messenger RNA in the rat.

To examine the effects of serum calcium concentrations on PTH biosynthesis, rats were made hyper- (serum total calcium, approximately 3.5 mM) or hypocalcemic (approximately 1.25 mM) and steady-state levels of PTH mRNA in parathyroid cells were measured by the primer extension method using a 32P-labe...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Yamamoto, M, Igarashi, T, Muramatsu, M, Fukagawa, M, Motokura, T, Ogata, E
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303782/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2493484/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113946
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