PC4/Tis7/IFRD1 Stimulates Skeletal Muscle Regeneration and Is Involved in Myoblast Differentiation as a Regulator of MyoD and NF-κB

In skeletal muscle cells, the PC4 (Tis7/Ifrd1) protein is known to function as a coactivator of MyoD by promoting the transcriptional activity of myocyte enhancer factor 2C (MEF2C). In this study, we show that up-regulation of PC4 in vivo in adult muscle significantly potentiates injury-induced rege...

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Detalhes bibliográficos
Main Authors: Micheli, Laura, Leonardi, Luca, Conti, Filippo, Maresca, Giovanna, Colazingari, Sandra, Mattei, Elisabetta, Lira, Sergio A., Farioli-Vecchioli, Stefano, Caruso, Maurizia, Tirone, Felice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037682/
https://ncbi.nlm.nih.gov/pubmed/21127072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162842
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