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Munc13-4 Restricts Motility of Rab27a-expressing Vesicles to Facilitate Lipopolysaccharide-induced Priming of Exocytosis in Neutrophils

LPS is an efficient sensitizer of the neutrophil exocytic response to a second stimulus. Although neutrophil exocytosis in response to pathogen-derived molecules plays an important role in the innate immune response to infections, the molecular mechanism underlying LPS-dependent regulation of neutro...

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Detalhes bibliográficos
Principais autores: Johnson, Jennifer L., Hong, Hong, Monfregola, Jlenia, Kiosses, William B., Catz, Sergio D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037678/
https://ncbi.nlm.nih.gov/pubmed/21148308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.184762
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