Proteasome-independent Degradation of Canonical NFκB Complex Components by the NleC Protein of Pathogenic Escherichia coli

The NFκB transcription factor is a key component of immune and inflammatory signaling as its activation induces the expression of antimicrobial reagents, chemokines, cytokines, and anti-apoptotic factors. Many pathogens encode effector proteins that target factors regulating NFκB activity and can pr...

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Autores principales: Mühlen, Sabrina, Ruchaud-Sparagano, Marie-Hélène, Kenny, Brendan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037621/
https://ncbi.nlm.nih.gov/pubmed/21148319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.172254
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