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GANP enhances the efficiency of mRNA nuclear export in mammalian cells

Nuclear export of mRNPs is mediated by transport factors such as NXF1 that bind mRNPs and mediate their translocation through the central channel of nuclear pores (NPC) using transient interactions with FG-nucleoporins. A number of nuclear factors enhance the efficiency of this process by concentrat...

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Bibliographic Details
Main Authors: Wickramasinghe, Vihandha O, Stewart, Murray, Laskey, Ronald A
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037533/
https://ncbi.nlm.nih.gov/pubmed/21326821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.1.5.12351
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