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Inhibition of kinesin-5, a microtubule-based motor protein, as a strategy for enhancing regeneration of adult axons
Developing neurons express a motor protein called kinesin-5 (also called kif11 or Eg5) which acts as a “brake” on the advance of the microtubule array during axonal growth. Pharmacological inhibition of kinesin-5 causes the developing axon to grow at a faster rate, retract less, and grow past cues t...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037443/ https://ncbi.nlm.nih.gov/pubmed/21166743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2010.01152.x |
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