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Inhibition of kinesin-5, a microtubule-based motor protein, as a strategy for enhancing regeneration of adult axons

Developing neurons express a motor protein called kinesin-5 (also called kif11 or Eg5) which acts as a “brake” on the advance of the microtubule array during axonal growth. Pharmacological inhibition of kinesin-5 causes the developing axon to grow at a faster rate, retract less, and grow past cues t...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lin, Shen, Liu, Mei, Son, Young-Jin, Himes, B. Timothy, Snow, Diane M., Yu, Wenqian, Baas, Peter W.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037443/
https://ncbi.nlm.nih.gov/pubmed/21166743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2010.01152.x
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