A phosphoprotein of Mr 47,000, defective in autosomal chronic granulomatous disease, copurifies with one of two soluble components required for NADPH:O2 oxidoreductase activity in human neutrophils.

The NADPH:O2 oxidoreductase (NADPH oxidase) of human neutrophils is converted from a dormant to an active state upon stimulation of the cells. We have studied the soluble fraction that is required for NADPH oxidase activation in a cell-free system. Human neutrophils were separated in a membrane-cont...

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Detaylı Bibliyografya

Yayımlandı:	J Clin Invest
Asıl Yazarlar:	Bolscher, B G, van Zwieten, R, Kramer, I M, Weening, R S, Verhoeven, A J, Roos, D
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Clinical Investigation 1989
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2537848/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113954
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