Replication of the human immunodeficiency virus 1 and impaired differentiation of T cells after in vitro infection of bone marrow immature T cells.

HIV-1 infection in vitro of normal bone marrow mononuclear cells (BMMC) depleted of mature T cells was studied. BMMC depleted of either CD3, CD2, or both could replicate HIV-1 irrespective of the presence of macrophages/monocytes. Infected bone marrow cells were shown to differentiate during the cul...

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Pubblicato in:	J Clin Invest
Autori principali:	Lunardi-Iskandar, Y, Nugeyre, M T, Georgoulias, V, Barré-Sinoussi, F, Jasmin, C, Chermann, J C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2563266/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113924
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