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HPV-DNA integration and carcinogenesis: putative roles for inflammation and oxidative stress

HPV-DNA integration into cellular chromatin is usually a necessary event in the pathogenesis of HPV-related cancer; however, the mechanism of integration has not been clearly defined. Breaks must be created in both the host DNA and in the circular viral episome for integration to occur, and studies...

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Bibliographic Details
Main Authors: Williams, Vonetta M, Filippova, Maria, Soto, Ubaldo, Duerksen-Hughes, Penelope J
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037184/
https://ncbi.nlm.nih.gov/pubmed/21318095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.10.73
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