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LOXL1 deficiency negatively impacts the biomechanical properties of the mouse vagina and supportive tissues

Mice deficient in lysyl oxidase-like1 protein (LOXL1(−/−)) develop pelvic organ prolapse (POP). We sought to determine the impact of LOXL1(−/−) on the biomechanical properties of the vagina and its supportive tissues tested as a complex. Tissues of nulliparous LOXL1(−/−) and age-matched wild type (W...

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Autores principales: Alperin, Marianna, Debes, Kristen, Abramowitch, Steven, Meyn, Leslie, Moalli, Pamela A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037182/
https://ncbi.nlm.nih.gov/pubmed/18265927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00192-008-0561-7
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