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Effects of acute ischemia in the dog on myocardial blood flow, beta receptors, and adenylate cyclase activity with and without chronic beta blockade.

We ligated the left anterior descending coronary artery for 1 or 2 h in 31 purebred beagles. We did not detect any changes in beta-adrenergic receptor density or affinity when normal and ischemic zones were compared, either in the subendocardium or in the subepicardium. In the ischemic zones, there...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Karliner, J S, Stevens, M B, Honbo, N, Hoffman, J I
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303703/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2563265/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113906
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