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Redirection of prostaglandin endoperoxide metabolism at the platelet-vascular interface in man.

Prostacyclin (PGI2) is an inhibitor of platelet function in vitro. We tested the hypothesis that PGI2 is formed in biologically active concentrations at the platelet-vascular interface in man and can be pharmacologically modulated to enhance its inhibitory properties. This became feasible when we de...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Nowak, J, FitzGerald, G A
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303692/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2643628/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113895
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