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SOD1 Limits Renal Microvascular Remodeling and Attenuates Arteriole and Blood Pressure Responses to Angiotensin II via Modulation of Nitric Oxide Bioavailability

Oxidative stress is associated with vascular remodeling and increased preglomerular resistance that are both implicated in the pathogenesis of renal and cardiovascular disease. Angiotensin II induces superoxide production which is metabolized by superoxide dismutase (SOD) or scavenged by nitric oxid...

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Bibliografiske detaljer
Main Authors: Carlström, Mattias, Lai, En Yin, Ma, Zufu, Steege, Andreas, Patzak, Andreas, Eriksson, Ulf J., Lundberg, Jon O., Wilcox, Christopher S., Persson, A. Erik G.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036793/
https://ncbi.nlm.nih.gov/pubmed/20876452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.159301
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