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The Label-Free Unambiguous Detection and Symbolic Display of Single Nucleotide Polymorphisms on DNA Origami

Single Nucleotide Polymorphisms (SNPs) are the most common genetic variation in the human genome. Kinetic methods based on branch migration have proved successful for detecting SNPs because a mispair inhibits the progress of branch migration in the direction of the mispair. We have combined the effe...

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Main Authors: Subramanian, Hari K. K., Chakraborty, Banani, Sha, Ruojie, Seeman, Nadrian C.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036790/
https://ncbi.nlm.nih.gov/pubmed/21235216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl104555t
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