False negative rates in Drosophila cell-based RNAi screens: a case study

BACKGROUND: High-throughput screening using RNAi is a powerful gene discovery method but is often complicated by false positive and false negative results. Whereas false positive results associated with RNAi reagents has been a matter of extensive study, the issue of false negatives has received les...

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Bibliografiske detaljer
Main Authors: Booker, Matthew, Samsonova, Anastasia A, Kwon, Young, Flockhart, Ian, Mohr, Stephanie E, Perrimon, Norbert
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036618/
https://ncbi.nlm.nih.gov/pubmed/21251254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-50
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