Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures.

PTH was studied for its effects on bone formation in cultured rat calvariae. 0.01-10 nM PTH stimulated [3H]thymidine incorporation into DNA by up to 4.8-fold. Although continuous treatment with PTH for 24-72 h inhibited [3H]proline incorporation into collagen, transient (24 h) treatment enhanced [3H...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Canalis, E, Centrella, M, Burch, W, McCarthy, T L
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2910920/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113885
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