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Biliary copper excretion by hepatocyte lysosomes in the rat. Major excretory pathway in experimental copper overload.

We investigated the hypothesis that lysosomes are the main source of biliary copper in conditions of hepatic copper overload. We used a rat model of oral copper loading and studied the relationship between the biliary output of copper and lysosomal hydrolases. Male Sprague-Dawley rats were given tap...

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Bibliografische gegevens
Hoofdauteurs: Gross, J B, Myers, B M, Kost, L J, Kuntz, S M, LaRusso, N F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1989
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC303639/
https://ncbi.nlm.nih.gov/pubmed/2910913
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