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Interleukin-4 activates androgen receptor through CBP/p300

BACKGROUND: Aberrant activation of androgen receptor (AR) plays an important role in the progression of castration resistant prostate cancer. Interleukin-4 (IL-4) enhances AR activation in the absence of androgen and stimulates castration resistant growth of androgen-sensitive prostate cancer cells....

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Detalles Bibliográficos
Main Authors: Lee, Soo Ok, Chun, Jae Yeon, Nadiminty, Nagalakshmi, Lou, Wei, Feng, Siting, Gao, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035998/
https://ncbi.nlm.nih.gov/pubmed/18819102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20865
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