Oral priming with Salmonella Typhi vaccine strain CVD 909 followed by parenteral boost with the S. Typhi Vi capsular polysaccharide vaccine induces CD27(+) IgD(−)S. Typhi specific IgA and IgG B memory cells in humans

Attenuated live oral typhoid vaccine candidate CVD 909 constitutively expresses Salmonella Typhi capsular polysaccharide antigen (Vi). A randomized, double-blind, heterologous prime-boost clinical study was conducted to determine whether immunity to licensed parenteral Vi vaccine could be enhanced b...

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Detalhes bibliográficos
Main Authors: Wahid, Rezwanul, Pasetti, Marcela F., Maciel, Milton, Simon, Jakub K., Tacket, Carol O., Levine, Myron M., Sztein, Marcelo B
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035995/
https://ncbi.nlm.nih.gov/pubmed/21146460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.11.006
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