High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias

In order to develop a xenograft model to determine the efficacy of new therapies against primary human precursor-B acute lymphoblastic leukemia (ALL) stem cells (LSCs), we used the highly immunodeficient non-obese diabetic (NOD).Cg-Prkdc(scid)IL2rg(tmlWjl)/SzJ (NOD-severe combined immune deficient (...

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Hlavní autoři: Morisot, S, Wayne, A S, Bohana-Kashtan, O, Kaplan, I M, Gocke, C D, Hildreth, R, Stetler-Stevenson, M, Walker, R L, Davis, S, Meltzer, P S, Wheelan, S J, Brown, P, Jones, R J, Shultz, L D, Civin, C I
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035974/
https://ncbi.nlm.nih.gov/pubmed/20739953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.184
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