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Global regulation of H2A.Z localization by the INO80 chromatin remodeling enzyme is essential for genome integrity

INO80 is an evolutionarily conserved, ATP-dependent chromatin remodeling enzyme that plays roles in transcription, DNA repair, and replication. Here, we show that yeast INO80 facilitates these diverse processes at least in part by controlling genome-wide distribution of the histone variant H2A.Z. In...

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Bibliographische Detailangaben
Hauptverfasser: Papamichos-Chronakis, Manolis, Watanabe, Shinya, Rando, Oliver J., Peterson, Craig L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035940/
https://ncbi.nlm.nih.gov/pubmed/21241891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.12.021
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