Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction

The overall effect of brain zinc (Zn(2+)) in the progression and development of Alzheimer's disease (AD) is still not completely understood. Although an excess of Zn(2+) can exacerbate the pathological features of AD, a deficit of Zn(2+) intake has also been shown to increase the volume of amyl...

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Détails bibliographiques
Auteurs principaux: Corona, C, Masciopinto, F, Silvestri, E, Viscovo, A Del, Lattanzio, R, Sorda, R La, Ciavardelli, D, Goglia, F, Piantelli, M, Canzoniero, L M T, Sensi, S L
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035902/
https://ncbi.nlm.nih.gov/pubmed/21368864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.73
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