Discovery of Potent Kisspeptin Antagonists Delineate Physiological Mechanisms of Gonadotropin Regulation

Neurons that produce gonadotropin-releasing hormone (GnRH) are the final common pathway by which the brain regulates reproduction. GnRH neurons are regulated by an afferent network of kisspeptin-producing neurons. Kisspeptin binds to its cognate receptor on GnRH neurons and stimulates their activity...

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Detalhes bibliográficos
Main Authors: Roseweir, Antonia K., Kauffman, Alexander S., Smith, Jeremy T., Guerriero, Kathryn A., Morgan, Kevin, Pielecka-Fortuna, Justyna, Pineda, Rafael, Gottsch, Michelle L., Tena-Sempere, Manuel, Moenter, Suzanne M., Terasawa, Ei, Clarke, Iain J., Steiner, Robert A., Millar, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035813/
https://ncbi.nlm.nih.gov/pubmed/19321788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5740-08.2009
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