A common neoepitope is created when the reactive center of C1-inhibitor is cleaved by plasma kallikrein, activated factor XII fragment, C1 esterase, or neutrophil elastase.

The reactive center of C1-inhibitor, a plasma protease inhibitor that belongs to the serpin superfamily, is located on a peptide loop which is highly susceptible to proteolytic cleavage. With plasma kallikrein, C1s and beta-Factor XIIa, this cleavage occurs at the reactive site residue P1 (Arg444);...

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Detaylı Bibliyografya

Yayımlandı:	J Clin Invest
Asıl Yazarlar:	de Agostini, A, Patston, P A, Marottoli, V, Carrel, S, Harpel, P C, Schapira, M
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Clinical Investigation 1988
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303566/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2457036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113650
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