A Local Proinflammatory Signalling Loop Facilitates Adverse Age-Associated Arterial Remodeling

BACKGROUND: The coincidence of vascular smooth muscle cells (VSMC) infiltration and collagen deposition within a diffusely thickened intima is a salient feature of central arterial wall inflammation that accompanies advancing age. However, the molecular mechanisms involved remain undefined. METHODOL...

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Hlavní autoři: Wang, Mingyi, Spinetti, Gaia, Monticone, Robert E., Zhang, Jing, Wu, James, Jiang, Liqun, Khazan, Benjamin, Telljohann, Richard, Lakatta, Edward G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035650/
https://ncbi.nlm.nih.gov/pubmed/21347430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016653
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