Decreased membrane mechanical stability and in vivo loss of surface area reflect spectrin deficiencies in hereditary spherocytosis.

Whereas marked variations in the clinical manifestations of hereditary spherocytosis have long been recognized, we have only recently begun to define the molecular basis for this heterogeneity. An important unanswered question is whether decreased spectrin results in reduced membrane mechanical stab...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Chasis, J A, Agre, P, Mohandas, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3403720/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113640
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