Monitoring of fatty aldehyde dehydrogenase by formation of pyrenedecanoic acid from pyrenedecanal

Fatty aldehyde dehydrogenase (EC 1.2.1.48) converts long-chain fatty aldehydes to the corresponding acids. Deficiency in this enzyme causes the Sjogren Larsson Syndrome, a rare inherited disorder characterized by ichthyosis, spasticity, and mental retardation. Using a fluorescent aldehyde, pyrenedec...

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Main Authors: Keller, Markus A., Watschinger, Katrin, Golderer, Georg, Maglione, Manuel, Sarg, Bettina, Lindner, Herbert H., Werner-Felmayer, Gabriele, Terrinoni, Alessandro, Wanders, Ronald J. A., Werner, Ernst R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035519/
https://ncbi.nlm.nih.gov/pubmed/19965611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D002220
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