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Defect in the membrane expression of high affinity 72-kD Fc gamma receptors on phagocytic cells in four healthy subjects.

Three different receptors for the Fc portion of IgG (FcR) have been characterized on human leukocytes. We have identified four healthy members of one family, whose blood phagocytic cells lack functional 72 kD high-affinity FcRI. Their monocytes were unable to bind the Fc portion of mouse (m)-IgG2a a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Ceuppens, J L, Baroja, M L, Van Vaeck, F, Anderson, C L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303550/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2969920/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113634
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