Centromere-associated topoisomerase activity in bloodstream form Trypanosoma brucei

Topoisomerase-II accumulates at centromeres during prometaphase, where it resolves the DNA catenations that represent the last link between sister chromatids. Previously, using approaches including etoposide-mediated topoisomerase-II cleavage, we mapped centromeric domains in trypanosomes, early bra...

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Autori principali: Obado, Samson O., Bot, Christopher, Echeverry, Maria C., Bayona, Julio C., Alvarez, Vanina E., Taylor, Martin C., Kelly, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Nucleic Acid Enzymes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035458/
https://ncbi.nlm.nih.gov/pubmed/20864447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq839
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