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Mechanism of action of Escherichia coli heat stable enterotoxin in a human colonic cell line.

Escherichia coli heat stable enterotoxin (STa) caused Cl- secretion across T84 cell monolayers in a dose-dependent manner only when applied to the apical membrane surface and not when applied to the basolateral surface. Measurement of cAMP, cGMP, and free cytosolic Ca2+ in response to STa suggested...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Huott, P A, Liu, W, McRoberts, J A, Giannella, R A, Dharmsathaphorn, K
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1988
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303542/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2457034/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113626
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