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Biocontainment strategies for live lactic acid bacteria vaccine vectors
Stability is an important issue when engineering bacteria for use as live vaccine vectors. For the majority of live bacterial vaccines, the antigen-encoding gene is either plasmid located or integrated into the chromosome. Regardless, several safety concerns can be raised for both instances. One con...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035145/ https://ncbi.nlm.nih.gov/pubmed/21327129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.1.1.10594 |
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