Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease

Children with sickle cell disease (SCD) and strokes receive blood transfusion therapy for secondary stroke prevention; despite this, approximately 20% experience second overt strokes. Given this rate of second overt strokes and the clinical significance of silent cerebral infarcts, we tested the hyp...

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Detalhes bibliográficos
Main Authors: Hulbert, Monica L., McKinstry, Robert C., Lacey, JoAnne L., Moran, Christopher J., Panepinto, Julie A., Thompson, Alexis A., Sarnaik, Sharada A., Woods, Gerald M., Casella, James F., Inusa, Baba, Howard, Jo, Kirkham, Fenella J., Anie, Kofi A., Mullin, Jonathan E., Ichord, Rebecca, Noetzel, Michael, Yan, Yan, Rodeghier, Mark, DeBaun, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035071/
https://ncbi.nlm.nih.gov/pubmed/20940417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-261123
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