Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease

Children with sickle cell disease (SCD) and strokes receive blood transfusion therapy for secondary stroke prevention; despite this, approximately 20% experience second overt strokes. Given this rate of second overt strokes and the clinical significance of silent cerebral infarcts, we tested the hyp...

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Hlavní autoři: Hulbert, Monica L., McKinstry, Robert C., Lacey, JoAnne L., Moran, Christopher J., Panepinto, Julie A., Thompson, Alexis A., Sarnaik, Sharada A., Woods, Gerald M., Casella, James F., Inusa, Baba, Howard, Jo, Kirkham, Fenella J., Anie, Kofi A., Mullin, Jonathan E., Ichord, Rebecca, Noetzel, Michael, Yan, Yan, Rodeghier, Mark, DeBaun, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Clinical Trials and Observations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035071/
https://ncbi.nlm.nih.gov/pubmed/20940417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-261123
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