CTLs respond with activation and granule secretion when serving as targets for T-cell recognition

Cytotoxic T lymphocytes (CTLs) suppress T cell responses directed against their antigens regardless of their own T cell receptor (TCR) specificity. This makes the use of CTLs promising for tolerance induction in autoimmunity and transplantation. It has been established that binding of the CTL CD8 mo...

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Detalhes bibliográficos
Main Authors: Milstein, Oren, Hagin, David, Lask, Assaf, Reich-Zeliger, Shlomit, Shezen, Elias, Ophir, Eran, Eidelstein, Yaki, Afik, Ran, Antebi, Yaron E., Dustin, Michael L., Reisner, Yair
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035066/
https://ncbi.nlm.nih.gov/pubmed/21045195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-283770
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