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Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart.

Human heart failure is associated with a diminished contractile response to beta-adrenergic agonists. We hypothesized that alterations in the activity of a guanine nucleotide-binding regulatory protein (G protein) might be partially responsible for this abnormality. We therefore measured the activit...

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Bibliografische gegevens
Hoofdauteurs: Feldman, A M, Cates, A E, Veazey, W B, Hershberger, R E, Bristow, M R, Baughman, K L, Baumgartner, W A, Van Dop, C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1988
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC303493/
https://ncbi.nlm.nih.gov/pubmed/2839545
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