The FGF-2-Derived Peptide FREG Inhibits Melanoma Growth In Vitro and In Vivo

Previous data report that fibroblast growth factor-2 (FGF-2)-derived peptide FREG potently inhibits FGF-2-dependent angiogenesis in vitro and in vivo. Here, we show that FREG inhibits up to 70% in vitro growth and invasion/migration of smooth muscle and melanoma cells. Such inhibition is mediated by...

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Detalhes bibliográficos
Main Authors: Aguzzi, Maria S, Faraone, Debora, D'Arcangelo, Daniela, De Marchis, Francesco, Toietta, Gabriele, Ribatti, Domenico, Parazzoli, Alberto, Colombo, Paolo, Capogrossi, Maurizio C, Facchiano, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034841/
https://ncbi.nlm.nih.gov/pubmed/20924364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.211
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