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Effects of corticotropin-releasing hormone and dexamethasone on proopiomelanocortin messenger RNA level in human corticotroph adenoma cells in vitro.

The effects of corticotropin-releasing hormone (CRH) and dexamethasone on proopiomelanocortin (POMC) mRNA levels in cultured pituitary adenoma cells were studied in 10 patients with Cushing's disease. As a control, POMC mRNA levels in cells from nonadenomatous tissues were examined in four patients....

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Published in:J Clin Invest
Main Authors: Suda, T, Tozawa, F, Yamada, M, Ushiyama, T, Tomori, N, Sumitomo, T, Nakagami, Y, Demura, H, Shizume, K
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1988
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303483/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2839542/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113557
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