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Evidence that the primary binding site of von Willebrand factor that mediates platelet adhesion on subendothelium is not collagen.

We have studied the binding of von Willebrand factor to extracellular matrices of endothelial cells and to the vessel wall of human umbilical arteries in relation to its function in supporting platelet adhesion. CLB-RAg 201, an MAb against von Willebrand factor, completely inhibits the binding of vo...

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Détails bibliographiques
Auteurs principaux: de Groot, P G, Ottenhof-Rovers, M, van Mourik, J A, Sixma, J J
Format: Artigo
Langue:Inglês
Publié: 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC303477/
https://ncbi.nlm.nih.gov/pubmed/2839553
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