Use of vaccinia virus vectors to study protein processing in human disease. Normal nerve growth factor processing and secretion in cultured fibroblasts from patients with familial dysautonomia.

Familial dysautonomia is a hereditary disorder that affects autonomic and sensory neurons. Nerve growth factor (NGF) is required for the normal development of sympathetic and sensory neurons and it has been postulated that an abnormality involving NGF may be responsible for familial dysautonomia. Pr...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Edwards, R H, Rutter, W J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3392215/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113599
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