Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells

BACKGROUND: Cytotoxic cells of the immune system have evolved a lysosomal compartment to store and mobilize effector molecules. In T lymphocytes and NK cells, the death factor FasL is one of the characteristic marker proteins of these so-called secretory lysosomes, which combine properties of conven...

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Main Authors: Schmidt, Hendrik, Gelhaus, Christoph, Nebendahl, Melanie, Lettau, Marcus, Lucius, Ralph, Leippe, Matthias, Kabelitz, Dietrich, Janssen, Ottmar
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034720/
https://ncbi.nlm.nih.gov/pubmed/21255389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-9-4
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