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Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice
BACKGROUND: The mechanism by which HIV infection leads to a selective depletion of CD4 cells leading to immunodeficiency remains highly debated. Whether the loss of CD4 cells is a direct consequence of virus infection or bystander apoptosis of uninfected cells is also uncertain. RESULTS: We have add...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034703/ https://ncbi.nlm.nih.gov/pubmed/21255440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-34 |
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