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Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus

CTP synthase catalyzes the last committed step in de novo pyrimidine-nucleotide biosynthesis. Active CTP synthase is a tetrameric enzyme composed of a dimer of dimers. The tetramer is favoured in the presence of the substrate nucleotides ATP and UTP; when saturated with nucleotide, the tetramer comp...

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Autors principals: Lauritsen, Iben, Willemoës, Martin, Jensen, Kaj Frank, Johansson, Eva, Harris, Pernille
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034608/
https://ncbi.nlm.nih.gov/pubmed/21301086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110052334
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