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Neuromuscular junction toxicity with tandutinib induces a myasthenic-like syndrome

BACKGROUND: Tandutinib (MLN 518, Millennium Pharmaceuticals, Cambridge, MA) is an orally active multitargeted tyrosine kinase inhibitor that is currently under evaluation for the treatment of glioblastoma and has been used in the treatment of leukemia. In prior clinical and animal studies, a dose-de...

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Hlavní autoři: Lehky, T.J., Iwamoto, F.M., Kreisl, T.N., Floeter, M.K., Fine, H.A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034397/
https://ncbi.nlm.nih.gov/pubmed/21242491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182074a69
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