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Phase I trial of pegylated interferon-α-2b in young patients with plexiform neurofibromas
OBJECTIVE: Interferon has antiproliferative and antiangiogenic properties. We sought to evaluate preliminary efficacy and determine the recommended phase II dose (RP2D) for pegylated interferon-α-2b (PI) in patients with unresectable progressive or symptomatic plexiform neurofibromas (PN). METHODS:...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034394/ https://ncbi.nlm.nih.gov/pubmed/21242495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318207b031 |
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