Subsets of Memory Cytotoxic T Lymphocytes Elicited by Vaccination Influence the Efficiency of Secondary Expansion In Vivo

Vaccine-elicited cytotoxic T lymphocytes (CTL) should be long-lived memory cells that can rapidly expand in number following re-exposure to antigen. The present studies were initiated to analyze the ability of plasmid interleukin-12 (IL-12) to augment CTL responses in mice when delivered during the...

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Autors principals: Seaman, Michael S., Peyerl, Fred W., Jackson, Shawn S., Lifton, Michelle A., Gorgone, Darci A., Schmitz, Jörn E., Letvin, Norman L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC303428/
https://ncbi.nlm.nih.gov/pubmed/14671102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.206-215.2004
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