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Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to the prolonged injury

BACKGROUND AND PURPOSE: Notch receptors (1-4) are membrane proteins that, upon ligand stilumation, release their cytoplasmic domains to serve as transcription factors. Notch-2 promotes proliferation both during development and cancer but its role in response to ischemic injury is less well understoo...

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Autors principals: Albéri, L., Chi, Z., Kadam, S.D., Mulholland, J.D., Dawson, V.L., Gaiano, N., Comi, A.M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034189/
https://ncbi.nlm.nih.gov/pubmed/20876509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.595298
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