Modulation of the glyoxalase system in the aging model Podospora anserina: effects on growth and lifespan

The eukaryotic glyoxalase system consists of two enzymatic components, glyoxalase I (lactoylglutathione lyase) and glyoxalase II (hydroxyacylglutathione hydrolase). These enzymes are dedicated to the removal of toxic α-oxoaldehydes like methylglyoxal (MG). MG is formed as a by-product of glycolysis...

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Autors principals: Scheckhuber, Christian Q., Mack, Sandra J., Strobel, Ingmar, Ricciardi, Filomena, Gispert, Suzana, Osiewacz, Heinz D.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2010
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034185/
https://ncbi.nlm.nih.gov/pubmed/21212464
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