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Neonatal exposure to genistein adversely impacts the ontogeny of hypothalamic kisspeptin signaling pathways and ovarian development in the peripubertal female rat

Neonatal genistein exposure at physiologically relevant levels advances vaginal opening, disrupts ovarian development and defeminizes the ontogeny of kisspeptin signaling pathways in the female rat hypothalamus. Neonatal exposure to estrogenic endocrine disrupting compounds (EDCs) can advance pubert...

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書誌詳細
主要な著者: Losa, Sandra M, Todd, Karina L, Sullivan, Alana W, Cao, Jinyan, Mickens, Jillian A, Patisaul, Heather B
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034101/
https://ncbi.nlm.nih.gov/pubmed/20951797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2010.10.002
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