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Neonatal exposure to genistein adversely impacts the ontogeny of hypothalamic kisspeptin signaling pathways and ovarian development in the peripubertal female rat

Neonatal genistein exposure at physiologically relevant levels advances vaginal opening, disrupts ovarian development and defeminizes the ontogeny of kisspeptin signaling pathways in the female rat hypothalamus. Neonatal exposure to estrogenic endocrine disrupting compounds (EDCs) can advance pubert...

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Detalhes bibliográficos
Main Authors: Losa, Sandra M, Todd, Karina L, Sullivan, Alana W, Cao, Jinyan, Mickens, Jillian A, Patisaul, Heather B
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034101/
https://ncbi.nlm.nih.gov/pubmed/20951797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2010.10.002
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