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D-Galactose Effectiveness in Modeling Aging and Therapeutic Antioxidant Treatment in Mice

Accumulating evidence suggests that mitochondrial dysfunction and oxidative stress play major roles in aging. Chronic administration of D-galactose has been reported to cause deterioration of cognitive and motor skills that are similar to symptoms of aging and, therefore, is regarded as a model of a...

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Detalhes bibliográficos
Main Authors: Parameshwaran, Kodeeswaran, Irwin, Michael H., Steliou, Kosta, Pinkert, Carl A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034100/
https://ncbi.nlm.nih.gov/pubmed/21204654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2010.1020
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