Intrapatient Alterations in the Human Immunodeficiency Virus Type 1 gp120 V1V2 and V3 Regions Differentially Modulate Coreceptor Usage, Virus Inhibition by CC/CXC Chemokines, Soluble CD4, and the b12 and 2G12 Monoclonal Antibodies

We studied human immunodeficiency virus type 1 (HIV-1) chimeric viruses altering in their gp120 V1V2 and V3 envelope regions to better map which genetic alterations are associated with specific virus phenotypes associated with HIV-1 disease progression. The V1V2 and V3 regions studied were based on...

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Main Authors: Nabatov, Alexey A., Pollakis, Georgios, Linnemann, Thomas, Kliphius, Aletta, Chalaby, Moustapha I. M., Paxton, William A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC303404/
https://ncbi.nlm.nih.gov/pubmed/14671134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.524-530.2004
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